In the classroom of the Academy Supervisory Building, Yang Yu raised his hand and asked, "Doctor, why didn't Li Ang come to class?"

“He is doing a very important study.”

The doctor of mathematics science said to Wen Yuan with a stern face: "Not only today's class, you will not see him in the future for some time."

"ah?"

Yang Yu and others were stunned and asked subconsciously: "What research does it take so long? How could Jijiu agree to approve the fake for so long?"

"It's not a calculation anyway!"

Chao Wenyuan slapped the table, blew his beard and stared, muttering something in a low voice, "It's really a waste of resources if you don't come to study mathematics..."

———

Outside the Patent Office of the Academy, Hu Shang and Jingguo merchants wearing gorgeous silk clothes were holding stacks of flying money and banknotes to surround Su Feng, a Ph.D. in Science.

"Dr. Su Feng, where is that Li Xiaolangjun? Didn't you say you'll see it in the next few days?"

"Yes, Dr. Su Feng, our money is ready. Just wait for him to give permission and we will transport the goods back."

"Doctor, our caravan is eating horses in Chang'an City, and they spend money every day. I really can't wait. Please ask Li Xiaolangjun, please."

The big stack of flying money waving by the merchants made the disciples of the academy who were interns in the patent institute dizzy.

Su Feng had to bow and release the momentum of the monks and shook the crowd a little, "I'm really sorry, I can't help with this. Li Ang has been very busy for a while and has no outsiders. Everyone should go home and wait for the notification."

———

North of Chang'an City, Daming Palace and Hanxiang Hall.

"Doctor Li Xiao didn't come? Didn't you tell him that this is for the royal heir?"

Concubine Zheng, who was born in the five surnames and Qiwang, sat on a bench, gently caressed her belly, which was ten months pregnant, and scolded the eunuch kneeling in the hall.

"Sister, don't be angry, it's not good for the emperor in the belly."

Another Concubine Lu, who also came from the five surnames, comforted her softly, looked at the eunuch and said, "You go to the school again, and the imperial doctor said that the delivery date is in the past few days. Please ask Dr. Li Xiao to come to Daming Palace to take a look every day after school in the school.

Nothing will be delayed,

When the emperor's heir is born, the Zheng family will remember his kindness..."

As the concubine surnamed Lu spoke, she suddenly noticed the fearful expression on the eunuch's face. She paused for a moment and said hesitantly: "You haven't seen that doctor Li, or the school didn't let you in? Who came forward to stop you?"

"Yes...is a sacrificial wine."

The eunuch lowered his head and said tremblingly: "I asked me to give you a word to the two concubines."

The two concubines stood up together, "What do you mean?"

"All, be more peaceful."

———

In the afternoon, Chai Cuiqiao was picked up by the school carriage and jumped out of the carriage with a large bag of small bags.

"Young Master."

Chai Cuiqiao, who was unknown, glanced at the carriage that was quietly driving away, turned to look at Li Ang who was standing at the intersection, and said in confusion: "We are..."

"We will live in the palace in the next few days."

Li Ang smiled apologetically, took the package from Chai Cuiqiao's hand, and took her to an unknown pavilion at the foot of the back mountain.

The first floor of the pavilion is filled with a wide range of experimental equipment, and the second floor is a bedroom residence.

The Academy attaches great importance to blood abscess medicine.

The priest who received the news applied to the mountain chief and provided Li Ang with a whole pavilion as an experimental place. He also approved the holiday for a long time. He would not lose credits if he didn't attend courses such as Yu Lu and National History.

"What's this?"

Chai Cuiqiao, who put down the changing of laundry and toiletries, poked the flask on the table curiously.

"This is a distillation flask, this is a condensation tube, this is a vacuum conduit tube, this is a receiving bottle, this is a capillary..."

Li Ang introduced experimental instruments to Chai Cuiqiao as clearly as he learned. These things were made by monks from the academy using their mind power and hot glass.

"What about this?"

Chai Cuiqiao pointed to a huge metal device with a cylindrical structure next to the wooden table.

“Simple circulating water vacuum pump.”

Li Ang smiled and said, "The impeller rotor is installed in the eccentricity of the cylindrical pump housing, and the blades of the rotor are tilted forward.

The pump body is filled with an appropriate amount of water as working fluid. When the impeller rotor rotates, the working water will form a water ring that swirls along the pump shell under centrifugation.

There is a certain space between the closed rotating water ring and the impeller rotor. When the rotation cycle repeats, the air can be pumped out.

Due to the simplicity of conditions, I could only let the doctors in the Palace of Academics design into a human rotation form.

The faster you turn, the higher the efficiency of pumping air."

"Well...."

Shibashi blinked, "What is the function of this...pump?"

"Reduce pressure, or even create a vacuum."

Li Ang waved his hand and said casually: "Of course, in this experiment, its main function is to perform decompression distillation.

And what is distilled..."

Li Ang brought a large bag of things from under the table and threw them on the table.

"This is..."

Shibashi said in shock: "Garlic?"

"That's right."

Li Ang smiled and said, "The antibacterial ingredient that solves blood abscess, or infection and inflammation, is in the garlic."

Diallylthiosulfinate, or allicin, is an organic sulfur compound.

It is not an antibiotic, but a broad-spectrum antibacterial drug.

It has inhibitory and killing effects on a variety of cocci, pertussis, diphtheria, dysentery, typhoid, paratyphoid, tuberculosis, etc.

It can even deal with a variety of fungi, viruses, and even amoeba protozoa that can cause meningitis, keratitis, and pinworms that are parasitic in the intestines.

Allicin can be used both on and off the surface, with less side effects and is not easy to cause the corresponding fungi or bacteria to develop resistance - because its bactericidal mechanism is mainly to directly destroy enzymes containing thiol groups.

It is difficult for fungi and bacteria to mutate and crack them.

The most common purulent cocci, Staphylococcus, is within the range of allicin killing.

Considering the relative difficulty in producing another antibiotic, penicillin, allicin can almost be said to be the easiest antibacterial drug to obtain at this stage.

The only problem is how to make it.

Fresh garlic does not have allicin, but only allicin. When the garlic is cut or crushed, allicinase is activated, catalyzing the decomposition of allicin into allicin.

If you eat raw garlic, according to the effective dosage, you must eat at least a few kilograms and more than ten kilograms at a time.

It must be purified.

In the next few days, Li Ang and Chai Cuiqiao stayed in the pavilion, busy extracting allicin using various methods.

After experiments, there are two most feasible methods for extracting allicin at this stage.

1. Water vapor decompression distillation method.

First peel and wash the garlic, put it in a stone mortar and mash it, pour it into a glass container, pour it into distilled water and cover it with a lid to seal it.

Use a salt bath to heat it to enzymatically dissolve it.

Then, a vacuum pump of circulating water is used to perform water vapor decompression distillation.

After collecting the distillate, distillation is again under reduced pressure.

After several cycles, after obtaining the solution, put it in a simple refrigerator made of ice grids. Allicin is extremely unstable and loses its antibacterial activity when it encounters heat or alkali. The effective period of the room temperature environment is very short.

In addition, due to the rich and touching taste, it is impossible to compete for other antibacterial drugs in the memory of another world.

2. Ethanol extraction method.

Also peel, wash, mash, and slightly heat enzymatically dissolve the garlic, pour in different concentrations of ethanol, use the reflux tower to fully dissolve allicin in ethanol, wait for several hours, centrifuge the garlic slurry at a rate of more than 1,000 revolutions per minute, filter it with double-layer rice paper, and discard the garlic residue.

The filtrate was distilled under reduced pressure and repeated several times to obtain a solution.

The entire extraction process lasted for several days.

The exhausted master and servant finally smiled at the hundreds of test tubes containing light yellow oily liquid allicin on the table.

Condensing tube technology has been used in distilled liquor in the Academy before this.

Garlic can also find evidence support from previous medical books.

The only problem is that it smells too stinky, and the process of extracting allicin is simply too stinky.

It was like a food symposium between canned herring, stinky tofu, and Kiviak (food made from rotten seagull seals by the Eskimos).

Li Ang inexplicably recalled the sour smell of some common surgical cerebral diseases, and wondered if he was a surgeon specializing in the abdomen and intestines in another world.

Even if the windows are fully opened and the Qingfeng Talisman is always used to ventilate, both the master and servant feel that they can't hold it too much.

"Young Master, I'm so smelly."

Shibashi smelled his clothes and said with a sad face.

"It's okay, I'm very smelly."

Li Ang comforted him and asked Chai Chai to go back to Jinchengfang to wash and rest, while he carried a box of test tubes and stepped out of the pavilion.
Chapter completed!