This small episode happened, and the investigation team did not stop studying Vibrio. In fact, two days after Xiao Xiuer and Sophia miraculously recovered from the disease, bacterologist Koch and several doctors developed the principle of Vibrio's disease.

"A large number of Vibrio enters the human body. They are almost completely killed by the gastric acid secreted by the human body, but maybe several Vibrioes will safely arrive at the small intestine. They will secrete a toxin, pumping chloride ions out of the small intestine cells like a water pump. This result will cause the chloride ions to bind to the sodium ions in the small intestine cavity, and the cells will become a high-salt environment outside the cell, while the cells are low in salt. In order to maintain the balance of water and salt, the water of the cell will be lost to the outside of the cell, and the small intestine cells that lack water absorb water from other parts of the body and then discharge it to the small intestine cavity again. In just one day, the toxin can suck 6 liters of water from the human body through the small intestine cells, which explains why patients experience severe dehydration."

"Vibirobacteria also reproduces in large quantities while obtaining nutrients and energy. They flow into the river or sewers with the foreign matter discharged by the patient, forming pollution. The sailor discovered by Xiao Xiu'er was the first pathogen, but the contamination was definitely not just the water he brought back. He himself became a breeding ground for bacteria."

Koch roughly studied the principle of Vibrio's pathogenicity and announced their research results to the investigation team with other researchers.

This discovery is an amazing progress.

Previously, Xiao Xiu'er's investigation blocked the spread of Vibrio, but there are still people who will inevitably get infected with the plague, or they will not know where to re-explode this type of plague in the future. The study of pathology is closer to the essence of the problem, and they can find treatment methods in a direction.

"According to this point, it is not just the water that is lost, but also the chlorine, sodium and potassium ions needed to maintain cell function. I understand why patients get numbness in their hands and feet, even muscle twitching, and organ failure." Xiao Xiuer has personally experienced the pain of severe diarrhea and has a better understanding of this disease.

She tried to propose a treatment method: "The pathogenic principle of Vibrio is very simple. It causes a large amount of water and ions to lose. If we can provide patients with a certain solution in time and replenish water and salts for the human body at the same time, can we effectively relieve symptoms, restore the body's water and salt balance, and give the human body's own immune system enough time to kill Vibrio or expel it?"

Many doctors and biology experts looked at each other, and then argued about the details one after another, and finally planned to conduct experiments according to Xiao Xiuer's suggestion.

The treatment proposed by Xiao Xiuer is not difficult, but is extremely simple. Compared with those diseases that require surgery, it is really simple if it is just supplementing the solution lacking due to severe diarrhea in the human body.

They soon began intense clinical experiments.

First of all, they need to configure a suitable solution, which must be as concentrated as the electrolyte lost by the patient as much as possible.

After strong request from the investigation team, the government provided them with salt, sugar and clean water.

"It's strange, how can the investigation team ask us for salt and sugar? Can they treat patients suffering from plague just with these common things?"

"Unless they intend to turn decay into magic, it is really unimaginable."

Regarding the request of the investigation team, officials in the government office were confused, such as monks, who could not understand the relationship between salt, sugar, water and plague.

"First boil the water to avoid Vibrio in the water, then add about 1 liter of water to 1 teaspoon of salt and 8 teaspoons of sugar."

After more detailed research, Xiao Xiuer and others developed a solution to treat Vibrio by using a very simple method.

Buckets of solutions were carried to the plague area. They asked the patients to drink this solution and treated the sick patients as clinical experimental products.

People who are still tortured by the plague are like seeing a savior, rushing to be guinea pigs and pouring this sweet solution.

In the face of a plague with a mortality rate of nearly 50%, even if they have a little more chance of survival, they are willing to try it.

A miracle happened. When people received this simple treatment, the mortality rate of patients who were still struggling decreased greatly, the diarrhea symptoms in most people were alleviated, and more and more patients finally healed themselves.

On the 10th day of the plague, the plague that broke out in Tianjin Wei ruthlessly claimed 500 lives was finally controlled and treated.

Chu Yun was on the 15th day of Tianjin Wei, and there were no new patients reported. As for the patients, except for the dead, the rest of the patients survived the difficulties with the help of normal saline and entered the stage of recovery.

The plague that was spreading throughout the city disappeared, and the order in the city was restored. People no longer feared the plague. As long as food and water were cooked, they could avoid infection with the plague.

Instant infection with the plague and there are oral solutions to treat the plague, which can greatly reduce the mortality rate caused by the plague.

Because of the outbreak of the plague and the implementation of the response strategy of boiling water, woodcutters and coal factories that sell firewood made a fortune from the plague business, and their firewood and coal became very popular.

Some poor people cannot afford a large amount of firewood and coal. In order to control the plague, the government also needs to distribute free firewood and coal to the poor.

After thousands of years of development in North China, the supply of firewood is getting smaller and smaller, and the demand for coal is greater. This epidemic has indirectly promoted the further development of the coal mining industry.

The matter is not over yet, and the aftermath measures are equally important. The investigation team needs to disinfect the wells and sewers infected with Vibrio, cremate the sick people who died of the plague, and concentrate on treating the patients' excrement.

However, when they finished the plague, the investigation team encountered an unprecedented difficulty.

When they planned to cremate the sick person who died of plague and prevent Vibrio from surviving, they were strongly resisted by the families of the deceased. They planned to let these people be buried in peace and were unwilling to cremate.

The incident became more and more serious. It was not until Chu Yun personally came forward to appease the people in the city, moved them with emotion, and explained them with reason, and asked the government to pay a pension to every family member that the pathogen was completely eliminated.

Chu Yun didn't think that people were generally conservative. He wanted the common people of this era to accept advanced common sense. The road was still very long and he could only take it slowly.

On the 30th day of the plague, just one month after the outbreak of the plague, the final work was over. After ensuring that there were no abnormalities, the investigation team prepared to return to the capital.
Chapter completed!